Dosimetry for Neutron Capture Therapy in JRR-4

An investigation into the potential applicability of gel dosimeters for dosimetry in boron neutron capture therapy

Background: The aim of this work was to establish how well gel dosimeters performed, as substitutes for brain tissue compared with standard phantom materials such as water, polymethyl-methacrylate (or PMMA), A150 plastic and TE- liquid phantom material for dosimetry of neutron beams in boron neutron capture therapy. Materials and Methods: Thermal neutron fluence, photon dose and epithermal neu...

Boron Neutron Capture Therapy for Glioblastoma: A Phase-I/II Clinical Trial at JRR-4

The Dosimetry Calculation for Boron Neutron Capture Therapy

BNCT incorporates the targeting principles of chemotherapy and the anatomical localization principles of conventional radiotherapy but with three distinct advantages:  Current boron compounds at the required concentrations are non-toxic.  The time interval between drug administration and neutron irradiation can be chosen to maximize the concentration differential between tumour and normal tis...

an investigation into the potential applicability of gel dosimeters for dosimetry in boron neutron capture therapy

background: the aim of this work was to establish how well gel dosimeters performed, as substitutes for brain tissue compared with standard phantom materials such as water, polymethyl-methacrylate (or pmma), a150 plastic and te- liquid phantom material for dosimetry of neutron beams in boron neutron capture therapy. materials and methods: thermal neutron fluence, photon dose and epithermal neut...

Finnish dosimetric practice for epithermal neutron beam dosimetry in boron neutron capture therapy

Boron neutron capture therapy (BNCT) is a form of chemically targeted radiotherapy that utilises the high neutron capture cross-section of boron-10 isotope to achieve a preferential dose increase in the tumour. The BNCT dosimetry poses a special challenge as the radiation dose absorbed by the irradiated tissues consists of several dose components with different relative biological effectiveness...